Sucralose is made from sucrose by a multi-step patented manufacturing process that selectively replaces three hydroxyl (molecularly bonded hydrogen and oxygen atoms) with chlorine atoms. This molecular change makes sucralose 600 times sweeter than sugar.

In 1999, sucralose was approved as a general-purpose sweetener in the U.S. Sucralose is sold under the brand name Splenda. The ingredients of the tabletop product are listed as “dextrose, maltodextrin and sucralose” on the packet.

Food manufacturers value sucralose because it is the most heat stable of the artificial sweeteners. This property has increased the introduction of sucralose into a broad range of foods and beverages previously sweetened with the other approved general-purpose artificial sweeteners.

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